Broccoli juice treated by high pressure, sulforaphane and indole-3-carbinol and their chemoprotective effects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14510%2F06%3A00031595" target="_blank" >RIV/00216224:14510/06:00031595 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Broccoli juice treated by high pressure, sulforaphane and indole-3-carbinol and their chemoprotective effects

Popis výsledku v původním jazyce

Numerous animal and epidemiological studies have demonstrated that consumption of cruciferous vegetables is inversely correlated with the cancer incidence. Using the shortterm mutagenicity test in vivo micronucleus test, we investigated inhibition of mutagenicity of IQ and MNU by influence of broccoli juice treated by high pressure method, 500 MPa for a period of 10 minutes. This technique of treatment suppresses the growth of microorganisms at simultaneous conservation of nutritionally important substances (vitamins, polyphenols, glucosinolates). We also investigated anticlastogenic aktivity of sulforaphane (SFN) and indol3carbinol (I3C). These two substances are found in inactive form (glucosinolates) in cruciferous vegetables Fourteendays application of broccoli juice and threedays application of I3C and SFN led to statistically significant inhibition of mutagenity.

Název v anglickém jazyce

Broccoli juice treated by high pressure, sulforaphane and indole-3-carbinol and their chemoprotective effects

Popis výsledku anglicky

Numerous animal and epidemiological studies have demonstrated that consumption of cruciferous vegetables is inversely correlated with the cancer incidence. Using the shortterm mutagenicity test in vivo micronucleus test, we investigated inhibition of mutagenicity of IQ and MNU by influence of broccoli juice treated by high pressure method, 500 MPa for a period of 10 minutes. This technique of treatment suppresses the growth of microorganisms at simultaneous conservation of nutritionally important substances (vitamins, polyphenols, glucosinolates). We also investigated anticlastogenic aktivity of sulforaphane (SFN) and indol3carbinol (I3C). These two substances are found in inactive form (glucosinolates) in cruciferous vegetables Fourteendays application of broccoli juice and threedays application of I3C and SFN led to statistically significant inhibition of mutagenity.

Druh

D - Stať ve sborníku

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Book of Abstracts and schedule, 44th EHPRG Meeting

ISBN

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ISSN

0895-7959

e-ISSN

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Počet stran výsledku

145

Strana od-do

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Název nakladatele

VUPP

Místo vydání

Praha

Místo konání akce

Praha

Datum konání akce

4. 9. 2006

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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