Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F11%3A43892172" target="_blank" >RIV/60461373:22330/11:43892172 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph

Popis výsledku v původním jazyce

Microbiological research is focused on solution of pathogen resistance problem. One of the potential solutions seems to be short cationic peptides naturally synthetized as a part of innate immunity. In our project larvae of the fleshly Neobellieria bullata were chosen as a source of these peptides. Several isolated fractions showed antimicrobial activity against bacteria and fungi. Tricine electrophoresis proved presence of low molecular peptide. MS analysis of antimicrobial active fractions determinedmolecular masses less than 10 kDa and the N-terminal sequencing gave us several sequences but not completed. The sequences do have very low similarity with peptides in the NCBI databases or with the database of antimicrobial peptides [2] and seem to be very unique

Název v anglickém jazyce

Purification and characterization of antimicrobial peptides from fleshfly larvae haemolymph

Popis výsledku anglicky

Microbiological research is focused on solution of pathogen resistance problem. One of the potential solutions seems to be short cationic peptides naturally synthetized as a part of innate immunity. In our project larvae of the fleshly Neobellieria bullata were chosen as a source of these peptides. Several isolated fractions showed antimicrobial activity against bacteria and fungi. Tricine electrophoresis proved presence of low molecular peptide. MS analysis of antimicrobial active fractions determinedmolecular masses less than 10 kDa and the N-terminal sequencing gave us several sequences but not completed. The sequences do have very low similarity with peptides in the NCBI databases or with the database of antimicrobial peptides [2] and seem to be very unique

Druh

C - Kapitola v odborné knize

CEP obor

CE - Biochemie

OECD FORD obor

—

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Science and Technology against Microbial Pathogens. Research, Development and Evaluation

ISBN

978-981-4354-85-1

Počet stran výsledku

5

Strana od-do

23-27

Počet stran knihy

432

Název nakladatele

World Scientific Publishing Co. Pte. Ltd.

Místo vydání

Singapore

Kód UT WoS kapitoly

—