Modulation of ethanol stress by resveratrol in Saccharomyces cerevisiae: Enzyme and lipid profile determination

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F16%3A43901671" target="_blank" >RIV/60461373:22330/16:43901671 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.jbiotec.2016.05.092" target="_blank" >http://dx.doi.org/10.1016/j.jbiotec.2016.05.092</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jbiotec.2016.05.092" target="_blank" >10.1016/j.jbiotec.2016.05.092</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Modulation of ethanol stress by resveratrol in Saccharomyces cerevisiae: Enzyme and lipid profile determination

Popis výsledku v původním jazyce

Saccharomyces cerevisiae is a widely used industrial microorganism. One of its possible applications is the production of ethanol, the main extracellular metabolite of alcohol fermentation. In high concentrations, ethanol acts as a stress factor that inhibits cellular growth and induces metabolic changes leading to the inhibition of ethanol production. One of the main responses to high ethanol concentrations is the induction of oxidative stress. The research is focused on the modulation of ethanol stress by known antioxidant resveratrol. Three traditional biotechnological yeast species of S. cerevisiae were exposed to different ethanol concentrations. The determination of lipid peroxidation products, fatty acid profile and changes in the activity of superoxide dismutase were used to determine the degree of ethanol induced cell damage, respectively resveratrol protective properties. The results showed that resveratrol have ability not only to mitigate the impact of ethanol yeasts, but also improve ethanol tolerance.

Název v anglickém jazyce

Modulation of ethanol stress by resveratrol in Saccharomyces cerevisiae: Enzyme and lipid profile determination

Popis výsledku anglicky

Saccharomyces cerevisiae is a widely used industrial microorganism. One of its possible applications is the production of ethanol, the main extracellular metabolite of alcohol fermentation. In high concentrations, ethanol acts as a stress factor that inhibits cellular growth and induces metabolic changes leading to the inhibition of ethanol production. One of the main responses to high ethanol concentrations is the induction of oxidative stress. The research is focused on the modulation of ethanol stress by known antioxidant resveratrol. Three traditional biotechnological yeast species of S. cerevisiae were exposed to different ethanol concentrations. The determination of lipid peroxidation products, fatty acid profile and changes in the activity of superoxide dismutase were used to determine the degree of ethanol induced cell damage, respectively resveratrol protective properties. The results showed that resveratrol have ability not only to mitigate the impact of ethanol yeasts, but also improve ethanol tolerance.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EI - Biotechnologie a bionika

OECD FORD obor

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Projekt

<a href="/cs/project/GA14-00227S" target="_blank" >GA14-00227S: Mikroorganizmy jako zdroje esenciálních mastných kyselin se zaměřením na extremofilní kmeny</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

JOURNAL OF BIOTECHNOLOGY

ISSN

0168-1656

e-ISSN

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Svazek periodika

231

Číslo periodika v rámci svazku

srpen

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

2

Strana od-do

19-20

Kód UT WoS článku

000380240300054

EID výsledku v databázi Scopus

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