Isoquercetin enzymatic production: A true story Response to the paper 'Zhua et al. [1]'

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F18%3A00495022" target="_blank" >RIV/61388971:_____/18:00495022 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.mcat.2018.04.033" target="_blank" >http://dx.doi.org/10.1016/j.mcat.2018.04.033</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mcat.2018.04.033" target="_blank" >10.1016/j.mcat.2018.04.033</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Isoquercetin enzymatic production: A true story Response to the paper 'Zhua et al. [1]'

Popis výsledku v původním jazyce

In this Letter to Editor, we correct and comment on the misleading information in the paper: the Dan Zhua, An Gong, Yan Xu, D'assise Kinfack Tsabing, Fuan Wu, Jun Wang: Isoquercitrin production from rutin catalyzed by naringinase under ultrasound irradiation.nJournal of Molecular Catalysis B: Enzymatic 134 (2016) 186-195' that describes the production of isoquercitrin (IQ, quercetin-3-β-D-glucopyranoside) from rutin (quercetin-3-β-D-glucopyranosyl-α-(1→6)-L-rhamnopyranoside) using enzymatic complex naringinase under ultrasound irradiation. Authors neglected presence of glucosidase in the naringinase preparation that results in the production of the mixture of IQ and quercetin and they failed to demonstrate the absence of quercetin e.g. by a co-injection of standard compounds, e.g. rutin, IQ and quercetin, but this has not been done. Therefore, authors could not conclude that they produced isoquercitrin, which makes the whole study invalid. Thorough analysis of this paper revealed ethical issues: the sum of indicators is sufficiently high to assume that the data were deliberately misappropriated to get the manuscript published despite ample publications on this subject with much superior results.n

Název v anglickém jazyce

Isoquercetin enzymatic production: A true story Response to the paper 'Zhua et al. [1]'

Popis výsledku anglicky

In this Letter to Editor, we correct and comment on the misleading information in the paper: the Dan Zhua, An Gong, Yan Xu, D'assise Kinfack Tsabing, Fuan Wu, Jun Wang: Isoquercitrin production from rutin catalyzed by naringinase under ultrasound irradiation.nJournal of Molecular Catalysis B: Enzymatic 134 (2016) 186-195' that describes the production of isoquercitrin (IQ, quercetin-3-β-D-glucopyranoside) from rutin (quercetin-3-β-D-glucopyranosyl-α-(1→6)-L-rhamnopyranoside) using enzymatic complex naringinase under ultrasound irradiation. Authors neglected presence of glucosidase in the naringinase preparation that results in the production of the mixture of IQ and quercetin and they failed to demonstrate the absence of quercetin e.g. by a co-injection of standard compounds, e.g. rutin, IQ and quercetin, but this has not been done. Therefore, authors could not conclude that they produced isoquercitrin, which makes the whole study invalid. Thorough analysis of this paper revealed ethical issues: the sum of indicators is sufficiently high to assume that the data were deliberately misappropriated to get the manuscript published despite ample publications on this subject with much superior results.n

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Molecular Catalysis

ISSN

2468-8231

e-ISSN

—

Svazek periodika

458

Číslo periodika v rámci svazku

Part A

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

3

Strana od-do

112-114

Kód UT WoS článku

000445982000015

EID výsledku v databázi Scopus

2-s2.0-85050630242