Terapeutické monitorování antiepileptic: srovnání mezi českou a švédskou fakultní nemocnicí

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61988987%3A17110%2F06%3AA0900JCE" target="_blank" >RIV/61988987:17110/06:A0900JCE - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Therapeutic Monitoring of Antiepileptic Drugs: A Comparison Between a Czech and a Swedish University Hospital.

Popis výsledku v původním jazyce

Plasma concentrations obtained routine therapeutic monitoring of antiepileptic drugs (AED( (N03 A ATC group) were compared in patients treated with one or several AED in the University Hospital in Ostrava, Czech Republic and Huddinge, Sweden. In monotherapy 33% of the analyses showed sub-therapeutic concentrations in Huddinge, compared to 38% in Ostrava. Eight percent of the analyses showed potentially toxic concentrations in Huddinge, but only 3% in Ostrava. Drug treatment of epilepsy in our two hospitals is surprisingly similar in terms of achieved plasma concnetrations, in spite of socioeconomic and cultural differences between our two countries. This may be explained by the long experiences with TDM in both hospitals, which has the inherent capacity to promote evidence based drug therapy.

Název v anglickém jazyce

Therapeutic Monitoring of Antiepileptic Drugs: A Comparison Between a Czech and a Swedish University Hospital.

Popis výsledku anglicky

Plasma concentrations obtained routine therapeutic monitoring of antiepileptic drugs (AED( (N03 A ATC group) were compared in patients treated with one or several AED in the University Hospital in Ostrava, Czech Republic and Huddinge, Sweden. In monotherapy 33% of the analyses showed sub-therapeutic concentrations in Huddinge, compared to 38% in Ostrava. Eight percent of the analyses showed potentially toxic concentrations in Huddinge, but only 3% in Ostrava. Drug treatment of epilepsy in our two hospitals is surprisingly similar in terms of achieved plasma concnetrations, in spite of socioeconomic and cultural differences between our two countries. This may be explained by the long experiences with TDM in both hospitals, which has the inherent capacity to promote evidence based drug therapy.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

THER DRUG MONIT

ISSN

0163-4356

e-ISSN

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Svazek periodika

28

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

4

Strana od-do

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Kód UT WoS článku

000241347600004

EID výsledku v databázi Scopus

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