Reakce rostlinných aminoxidas s N6-aminoalkylderiváty adeninu

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F04%3A00002168" target="_blank" >RIV/61989592:15310/04:00002168 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Reactions of plant amine oxidases with N6-aminoalkyl derivatives of adenine

Popis výsledku v původním jazyce

Plant copper-containing amine oxidases (CAOs, EC 1.4.3.6) catalyze the oxidation of various amines. Once there was a hypothesis that the enzymes could oxidize cytokinins - plant hormones derived from adenine1, however, it has been shown that they rathercause inhibition2. Here we report a study on the reactions of three plant CAOs from grass pea (Lathyrus sativus), lentil (Lens esculenta) and a Mediterranean shrub (Euphorbia characias) with synthetic N6-aminoalkyl derivatives of adenine representing combined analogues of cytokinins and polyamines. The following compounds were prepared using an established method: N6-(3-aminopropyl)adenine, APAD; N6-(4-aminobutyl)adenine, ABAD; N6-(4-amino-trans-but-2-enyl)adenine, ATBAD; N6-(4-amino-cis-but-2-enyl)adenine, ACBAD and N6-(4-aminobut-2-ynyl)adenine, ABYAD. First, reaction rates of enzymatic oxidation were measured to decide between substrate and inhibitory properties. Two of the studied adenine derivatives were found to be substrates (ABA

Název v anglickém jazyce

Reactions of plant amine oxidases with N6-aminoalkyl derivatives of adenine

Popis výsledku anglicky

Plant copper-containing amine oxidases (CAOs, EC 1.4.3.6) catalyze the oxidation of various amines. Once there was a hypothesis that the enzymes could oxidize cytokinins - plant hormones derived from adenine1, however, it has been shown that they rathercause inhibition2. Here we report a study on the reactions of three plant CAOs from grass pea (Lathyrus sativus), lentil (Lens esculenta) and a Mediterranean shrub (Euphorbia characias) with synthetic N6-aminoalkyl derivatives of adenine representing combined analogues of cytokinins and polyamines. The following compounds were prepared using an established method: N6-(3-aminopropyl)adenine, APAD; N6-(4-aminobutyl)adenine, ABAD; N6-(4-amino-trans-but-2-enyl)adenine, ATBAD; N6-(4-amino-cis-but-2-enyl)adenine, ACBAD and N6-(4-aminobut-2-ynyl)adenine, ABYAD. First, reaction rates of enzymatic oxidation were measured to decide between substrate and inhibitory properties. Two of the studied adenine derivatives were found to be substrates (ABA

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2004

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Universitatis Palackianae Olomucensis, Facultas Rerum Naturalium, Chemica

ISSN

0232-0061

e-ISSN

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Svazek periodika

43

Číslo periodika v rámci svazku

S

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

275

Strana od-do

44-45

Kód UT WoS článku

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EID výsledku v databázi Scopus

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