Methods of speciation analysis of arsenic in food and nutritional supplements by liquid chromatography inductively coupled plasma mass spectrometry (ICP-MS)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F12%3A33143252" target="_blank" >RIV/61989592:15310/12:33143252 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Methods of speciation analysis of arsenic in food and nutritional supplements by liquid chromatography inductively coupled plasma mass spectrometry (ICP-MS)

Popis výsledku v původním jazyce

Speciation analysis plays an important role in analysis of food and food supplements. Food is the most obvious mean of transport for toxic elements to enter the human body. The identification and determination of the element species is necessary for an accurate risk assessment. While the toxic inorganic arsenic (AsIII and AsV) have been proven as carcinogenic compounds, methylated forms of arsenic such as methylarsenic acid (MMA) and dimethylarsenic acid (DMA) are significantly less toxic. Finally, other well-known species such arsenobetaine (AsB), arsenocholine (AsC) and arsenosugars (AsSs) are considered to be non-toxic. This review focuses on basic principles of HPLC and advantages and limitations of using ICP-MS as a detector for arsenic speciation. Important aspects of analytical procedures used in analysis of food and food supplements including column, extraction method, mobile phases and separation conditions and validation parameters are also presented.

Název v anglickém jazyce

Methods of speciation analysis of arsenic in food and nutritional supplements by liquid chromatography inductively coupled plasma mass spectrometry (ICP-MS)

Popis výsledku anglicky

Speciation analysis plays an important role in analysis of food and food supplements. Food is the most obvious mean of transport for toxic elements to enter the human body. The identification and determination of the element species is necessary for an accurate risk assessment. While the toxic inorganic arsenic (AsIII and AsV) have been proven as carcinogenic compounds, methylated forms of arsenic such as methylarsenic acid (MMA) and dimethylarsenic acid (DMA) are significantly less toxic. Finally, other well-known species such arsenobetaine (AsB), arsenocholine (AsC) and arsenosugars (AsSs) are considered to be non-toxic. This review focuses on basic principles of HPLC and advantages and limitations of using ICP-MS as a detector for arsenic speciation. Important aspects of analytical procedures used in analysis of food and food supplements including column, extraction method, mobile phases and separation conditions and validation parameters are also presented.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Universitatis Palackianae Olomucensis, Facultas Rerum Naturalium, Chemica

ISSN

0232-0061

e-ISSN

—

Svazek periodika

52

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

22

Strana od-do

1-22

Kód UT WoS článku

—

EID výsledku v databázi Scopus

—