On-line two-dimensional liquid chromatography-tandem mass spectrometric determination of estrogens in sediments

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F11%3A00184991" target="_blank" >RIV/62156489:43210/11:00184991 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

On-line two-dimensional liquid chromatography-tandem mass spectrometric determination of estrogens in sediments

Popis výsledku v původním jazyce

The development of an on-line system for the simultaneous determination of alpha-estradiol,beta-estradiol, estrone and 17 alpha-ethynylestradiol in river sediments is described. The analytes were extracted from sediments by microwave-assisted extraction.A crude extract was directly analysed by a heart-cutting two dimensional high-performance liquid chromatography-ion trap-tandem mass spectrometry with an atmospheric pressure photoionization source operating in the positive mode. The method shows excellent performance in terms of accuracy, precision, and sensitivity. The accuracy of each estrogen was in the range of 98.8-107.1%. Intra-batch and inter-batch precisions were in the range of 6.2-7.0% and 8.3-9.5%, respectively. The limits of detection ranged from 90 to 250 pg g(-1). A significant reduction in the total analysis time and a reduction in sample manipulation are the main advantages of the proposed method. Finally, the method was applied on real sediment samples. (C) 2011 Elsev

Název v anglickém jazyce

On-line two-dimensional liquid chromatography-tandem mass spectrometric determination of estrogens in sediments

Popis výsledku anglicky

The development of an on-line system for the simultaneous determination of alpha-estradiol,beta-estradiol, estrone and 17 alpha-ethynylestradiol in river sediments is described. The analytes were extracted from sediments by microwave-assisted extraction.A crude extract was directly analysed by a heart-cutting two dimensional high-performance liquid chromatography-ion trap-tandem mass spectrometry with an atmospheric pressure photoionization source operating in the positive mode. The method shows excellent performance in terms of accuracy, precision, and sensitivity. The accuracy of each estrogen was in the range of 98.8-107.1%. Intra-batch and inter-batch precisions were in the range of 6.2-7.0% and 8.3-9.5%, respectively. The limits of detection ranged from 90 to 250 pg g(-1). A significant reduction in the total analysis time and a reduction in sample manipulation are the main advantages of the proposed method. Finally, the method was applied on real sediment samples. (C) 2011 Elsev

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GAP503%2F10%2F0975" target="_blank" >GAP503/10/0975: Vysoce selektivní nanostrukturované imprinty pro stanovení endokrinních disruptorů v životním prostředí</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Chromatography A

ISSN

0021-9673

e-ISSN

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Svazek periodika

1218

Číslo periodika v rámci svazku

16

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

2292-2300

Kód UT WoS článku

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EID výsledku v databázi Scopus

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