Occurrence of cell death in cancer cell line PC-3 after treatment of plumbagin

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F14%3A43908767" target="_blank" >RIV/62156489:43210/14:43908767 - isvavai.cz</a>

Výsledek na webu

<a href="https://mnet.mendelu.cz/mendelnet2014/mnet_2014_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2014/mnet_2014_full.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Occurrence of cell death in cancer cell line PC-3 after treatment of plumbagin

Popis výsledku v původním jazyce

The aim of this study, which is focused on occurrence of cell death in cancer cell line PC-3 after treatment of plumbagin is get information about distribution of normal, apoptotic and autophagic cells by exposure to plumbagin. Plumbagin is one of the simplest plant secondary metabolite of three major phylogenic families - Plumbaginaceae, Droseraceae and Ebenceae. Plumbagin assigns highly potent biological activities, for example antioxidant, antiinflammatory, anticancer, antibacterial and antifungal activities. Cancer cell line PC-3 is derived from the 4st degree of adenocarcinoma of prostate. The type of cell death is important for developing of new diagnostical approaches. In this study types of cell death were studied by using experiment which take48 hours. During this time cells were exposed to plumbagin, which cause one of type of cell death. Action of this metabolite was finished after certain hour depending on the number of sample and after that samples were analysed by light

Název v anglickém jazyce

Occurrence of cell death in cancer cell line PC-3 after treatment of plumbagin

Popis výsledku anglicky

The aim of this study, which is focused on occurrence of cell death in cancer cell line PC-3 after treatment of plumbagin is get information about distribution of normal, apoptotic and autophagic cells by exposure to plumbagin. Plumbagin is one of the simplest plant secondary metabolite of three major phylogenic families - Plumbaginaceae, Droseraceae and Ebenceae. Plumbagin assigns highly potent biological activities, for example antioxidant, antiinflammatory, anticancer, antibacterial and antifungal activities. Cancer cell line PC-3 is derived from the 4st degree of adenocarcinoma of prostate. The type of cell death is important for developing of new diagnostical approaches. In this study types of cell death were studied by using experiment which take48 hours. During this time cells were exposed to plumbagin, which cause one of type of cell death. Action of this metabolite was finished after certain hour depending on the number of sample and after that samples were analysed by light

Druh

D - Stať ve sborníku

CEP obor

EA - Morfologické obory a cytologie

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

MendelNet 2014: Proceedings of International Ph.D. Students Conference

ISBN

978-80-7509-174-1

ISSN

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e-ISSN

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Počet stran výsledku

5

Strana od-do

494-498

Název nakladatele

Mendelova univerzita v Brně

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

19. 11. 2014

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000362518300094