Study of various parameters that influence the content of exhaled breath condensate used in the diagnosis of gastroesophageal reflux disease

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F18%3A00492061" target="_blank" >RIV/68081715:_____/18:00492061 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14740/18:00104676

Výsledek na webu

<a href="http://dx.doi.org/10.1515/hjic-2018-0007" target="_blank" >http://dx.doi.org/10.1515/hjic-2018-0007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/hjic-2018-0007" target="_blank" >10.1515/hjic-2018-0007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Study of various parameters that influence the content of exhaled breath condensate used in the diagnosis of gastroesophageal reflux disease

Popis výsledku v původním jazyce

In this work, various parameters that influence the ionic content and pH of exhaled breath condensate in terms of the non-invasive diagnosis of gastroesophageal reflux disease were studied. Exhaled breath condensate samples were collected using a miniature and inexpensive sampling device. Capillary electrophoresis with contactless conductometric detection was used to monitor the ionic content of exhaled breath condensate. Background electrolyte composed of 20 mM of 2-(N-Morpholino)ethanesulfonic acid, 20 mM of L-Histidine, 2 mM of 18-Crown-6 and 30 mu M of cetyltrimethylammonium bromide facilitated the rapid separation of anions and cations, both in less than 2 minutes. The possibility of contamination of the exhaled breath condensate by saliva is discussed in detail. The day-to-day repeatability (n=5) of the ionic content and pH of the exhaled breath condensate was studied and was satisfactory, reflecting mainly the physiological variability.

Název v anglickém jazyce

Study of various parameters that influence the content of exhaled breath condensate used in the diagnosis of gastroesophageal reflux disease

Popis výsledku anglicky

In this work, various parameters that influence the ionic content and pH of exhaled breath condensate in terms of the non-invasive diagnosis of gastroesophageal reflux disease were studied. Exhaled breath condensate samples were collected using a miniature and inexpensive sampling device. Capillary electrophoresis with contactless conductometric detection was used to monitor the ionic content of exhaled breath condensate. Background electrolyte composed of 20 mM of 2-(N-Morpholino)ethanesulfonic acid, 20 mM of L-Histidine, 2 mM of 18-Crown-6 and 30 mu M of cetyltrimethylammonium bromide facilitated the rapid separation of anions and cations, both in less than 2 minutes. The possibility of contamination of the exhaled breath condensate by saliva is discussed in detail. The day-to-day repeatability (n=5) of the ionic content and pH of the exhaled breath condensate was studied and was satisfactory, reflecting mainly the physiological variability.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Hungarian Journal of Industrial Chemistry

ISSN

0133-0276

e-ISSN

—

Svazek periodika

46

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

HU - Maďarsko

Počet stran výsledku

6

Strana od-do

29-34

Kód UT WoS článku

000440079700007

EID výsledku v databázi Scopus

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