RNAi and miRNA pathways in plants I - molecular mechanisms

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F19%3A00523492" target="_blank" >RIV/68378050:_____/19:00523492 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

RNAi and miRNA pathways in plants I - molecular mechanisms

Popis výsledku v původním jazyce

RNA silencing denotes sequence-specific repression mediated by small RNAs. It includes post-transcriptional silencing mechanisms such as RNA interference (RNAi) and microRNA (miRNA) pathway or transcriptional silencing. RNA silencing regulates endogenous protein-coding gene expression, serves as a form of innate immunity targeting viruses, and protects genome integrity by repression of retrotransposons. This review provides overview of RNA silencing in flowering plants, from which come most published data. Plants have arguably the most complex RNA silencing system among eukaryots because of existence of many paralogs of key protein factors, which form in an intricate network of primary and secondary small RNAs, which mediate transcriptional and post-transcriptional effects. The first half of the review will provide a detailed catalogue of components of RNA silencing in plants while the second half will discuss the specific silencing mechanisms themselves and their biological roles, with a particular focus on the miRNA pathway, PTGS/VIG (plant’s equivalent of RNAi), and transcriptional gene silencing (TGS), which is a unique RNA silencing adaptation existing in plants. n

Název v anglickém jazyce

RNAi and miRNA pathways in plants I - molecular mechanisms

Popis výsledku anglicky

RNA silencing denotes sequence-specific repression mediated by small RNAs. It includes post-transcriptional silencing mechanisms such as RNA interference (RNAi) and microRNA (miRNA) pathway or transcriptional silencing. RNA silencing regulates endogenous protein-coding gene expression, serves as a form of innate immunity targeting viruses, and protects genome integrity by repression of retrotransposons. This review provides overview of RNA silencing in flowering plants, from which come most published data. Plants have arguably the most complex RNA silencing system among eukaryots because of existence of many paralogs of key protein factors, which form in an intricate network of primary and secondary small RNAs, which mediate transcriptional and post-transcriptional effects. The first half of the review will provide a detailed catalogue of components of RNA silencing in plants while the second half will discuss the specific silencing mechanisms themselves and their biological roles, with a particular focus on the miRNA pathway, PTGS/VIG (plant’s equivalent of RNAi), and transcriptional gene silencing (TGS), which is a unique RNA silencing adaptation existing in plants. n

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Projekt

<a href="/cs/project/LO1220" target="_blank" >LO1220: CZ-OPENSCREEN: Národní infrastruktura chemické biologie</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Introduction to RNAi and miRNA pathways

ISBN

978-80-246-4372-4

Počet stran výsledku

40

Strana od-do

1-339

Počet stran knihy

339

Název nakladatele

Karolinum

Místo vydání

Praha

Kód UT WoS kapitoly

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