Automated dynamic bioreactor for 2D endothelial structures

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F13%3A00214227" target="_blank" >RIV/68407700:21460/13:00214227 - isvavai.cz</a>

Výsledek na webu

<a href="http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6707315" target="_blank" >http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=6707315</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/EHB.2013.6707315" target="_blank" >10.1109/EHB.2013.6707315</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Automated dynamic bioreactor for 2D endothelial structures

Popis výsledku v původním jazyce

This work deals with construction of automated bioreactor that is used for 2D planar endothelial structures in optimized cultivation chamber. Designed bioreactor is controlled by industrial PC with FPGA card. It consists of proportionally controlled peristaltic pumps for cultivation media perfusion, necessary sensors and electronics for maintaining stable and repeatable operation during experiments, redundant power supply. FPGA card design gives deterministic control with implemented safety routines. Monitoring controlling software allows remote access. Endothelial cells are during experiments exposed to laminar flow at given shear stress, which helps to orient them in direction of flow and improves structure of cytoskeleton and intercellular connections. Results from cultivation experiments leads to establishing cultivation of 3D tubular structures and artificial vascular prostheses.

Název v anglickém jazyce

Automated dynamic bioreactor for 2D endothelial structures

Popis výsledku anglicky

This work deals with construction of automated bioreactor that is used for 2D planar endothelial structures in optimized cultivation chamber. Designed bioreactor is controlled by industrial PC with FPGA card. It consists of proportionally controlled peristaltic pumps for cultivation media perfusion, necessary sensors and electronics for maintaining stable and repeatable operation during experiments, redundant power supply. FPGA card design gives deterministic control with implemented safety routines. Monitoring controlling software allows remote access. Endothelial cells are during experiments exposed to laminar flow at given shear stress, which helps to orient them in direction of flow and improves structure of cytoskeleton and intercellular connections. Results from cultivation experiments leads to establishing cultivation of 3D tubular structures and artificial vascular prostheses.

Druh

D - Stať ve sborníku

CEP obor

JB - Senzory, čidla, měření a regulace

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

4th IEEE International Conference on e-Health and Bioengineering EHB 2013

ISBN

978-1-4799-2372-4

ISSN

—

e-ISSN

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Počet stran výsledku

4

Strana od-do

—

Název nakladatele

Gr. T. Popa University of Medicine and Pharmacy

Místo vydání

Iasi

Místo konání akce

Iasi

Datum konání akce

21. 11. 2013

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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